Friday, July 23, 2010

Mechanism of desroying antibody by some bacteria?

for example:Haemophillus influensae destroy IgA for making diasease

Mechanism of desroying antibody by some bacteria?
"Some pathogens produce enzymes that destroy antibodies.





Haemophilus influenzae [...], which can grow on the surfaces of the body, produce IgA proteases that inactivate secretory IgA by cleaving the molecule at the hinge region, detaching the Fc region of the immunoglobulin.


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