Friday, July 23, 2010

Exactly, how does penicillin kill the bacteria?

Please explain in PLAIN english

Exactly, how does penicillin kill the bacteria?
It breaks down the cell wall of the bacteria.
Reply:I'm allergic... it would kill ME.
Reply:It weakens the cell wall when the bacteria multiples.
Reply:It uses a 45 magnum.
Reply:Penicillin is made from fungi...


Have you ever been to the woods and seen mushrooms grow in circles and no other plants growing inside that circle?


Thats how penicillin works, it creates a deadly environment so the bacteria cant grow.





It was discoverd "accidenrially", the guy who invented penicillin went on vacation, he left his culture plates unwashed. When he came back a few weeks later, he noticed that something had "grown" on one of the culture plates. It was mould, and the bacteria were not growing around it!
Reply:Interferes with cell wall synthesis
Reply:It's great stuff that many are unfortunately allergic to. I'm allergic to a lot, but oddly not penicillin.








It works by inhibiting the formation of peptidoglycan cross links in the bacterial cell wall. The β-lactam moiety of penicillin binds to the enzyme (transpeptidase) that links the peptidoglycan molecules in bacteria, and this weakens the cell wall of the bacterium when it multiplies (in other words, the antibiotic causes cell cytolysis or death when the bacterium tries to divide).





It breaks down the components of the bacteria %26amp; attacks it that way. Details on this link:





http://en.wikipedia.org/wiki/Penicillin
Reply:Bacteria have a cell wall, unlike humans. They need it for structure and stability, we have a huge network of proteins outside of the cells that does this instead.





Penicillin prevents that cell wall from forming correctly. If the cell wall is not formed correctly the bacteria cannot survive. It will only affect growing bacteria, so it would not be good for slow growing bacteria.





Some strains of bacteria are resistant because they make a protein that breaks down penicillin.
Reply:Penicillin kills bacteria by disrupting cell wall synthesis. It does not break down the cell wall, it only inhibits the synthesis of it. Therefore, when bacteria replicates and makes a new cell wall that's when penicillin does it job. This is why some bacteria are not affected by penicillin, because they might not be in log phase (growth period) and no cell wall synthesis.





If you don't know this, bacteria (unlike animal cells) have a cell wall. If it is not intact, bacteria can still survive but not in all environments. For example, if bacteria are placed in a hypotonic (less solute concentration) environment, then water will come into the bacterial cells (because water flows from a low solute concentration to a high solute concentration) and the bacteria will lyse. Having a cell wall intact prevents this most of the time.
Reply:It kills the cell wall of the bacteria.


Did u no it is made out blue mold


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